This has happened to me on a number of occasions – and has always puzzled me. Working away in Dreamweaver and suddenly it dies – It won’t open again except for a few seconds when my workspace flashes before me and then vanishes.

My resolution was this  – I deduced that it was the site directory that I was currently working in that had caused issues (Yes didn’t need to be Sherlock Holmes to figure that one out).

1. So I renamed the directory
2. then created a new directory
3. Dreamweaver then opened
4. and I downloaded all my files again off the live server….

Now I know what really happened – as Norman explains what causes Dreamweaver to stop working is when a file in your site is exactly 8,192 bytes, or a multiple of this number. The fix is to find the file and just add a few characters to it, using notepad for example – then Dreamweaver will open again.

Read the full story at the link above. Interesting